There are quite a few quests in Titan Quest. If you see a person with an exclamation mark above their head, then you can speak with them to start or advance a quest.
There are 2 types of quests:
Main Quests: These missions tell the game's story. You must complete these to complete the game.
Side Quests: These quests are optional missions. There are many of them in each act. They have varied goals: kill unique monsters, speak with NPCs, deliver messages, etc.
Act I[]
- A Troubled Village (Road to Helos)
- Spartans at War (Village of Helos) (1 Skill Point)
- The Lost Dowry (Laconia Hills)
- The Ancient of War (Spartan War-Camp)
- The Poisoned Spring (Village of Tegea) (+75 / +150 / +200 Health)
- The Words of the Oracle (Spartan War-Camp)
- The Source of the Monsters (City of Delphi)
- A Proper Offering (City of Megara) (Resistance Bonus)
- The Good Centaur (Ambrossos Farmlands) (2 Attribute Points)
- A Master Blacksmith (Village of Ambrossos)
- Goods Abandoned (Village of Ambrossos)
- The Grieving Widow (City of Delphi)
- The Battle for Athens (Pythian Caves)
- The Order of Prometheus (Athenian Battleground)
- Under the Labyrinth (Athens Catacombs - Level V) (Second Inventory Bag)
Act II[]
- The Blindness of the Gods (City of Rhakotis)
- The Family Heirloom (City of Rhakotis)
- The Beast of Legend (Wadjet Canyons) (2 Skill Points)
- Plight of the Nile Farmers (Village of Sais)
- A Promethean Surrounded (The Lower Nile)
- The Invocation (Memphis Plaza) (2 Attribute Points)
- Lowest of the Low (Beggars Quarter)
- The High Priest's Request (Memphis Plaza)
- The Missing Brother (Memphis Plaza)
- Khufu's Curse (Giza Plateau)
- A Hidden Treasure (Fayum Oasis)
- Caravan Woes (Fayum Oasis)
- A Telkine in Egypt (Memphis Plaza) (2 Skill Points)
- The Sickle of Kronos (Temple of Seti)
Act III[]
- The Sickle of Kronos (Temple of Seti) (Third Inventory Bag)
- Hunt for the Sickle (Temple of Marduk, level 4)
- The Seeds of Destruction (Babylon Outskirts)
- A Gargantuan Yeti (Shangshung Village) (+100% Health for pets)
- Mystery in the Mountains (Shangshung Village)
- Caravan in Trouble (Natu La Ridge)
- The Child and the Raptor (Village of Guanzhong)
- Peng Problems (The Great Wall)
- Stalker in the Woods (Village of Zhidan)
- The Wealthy Collector (Village of Zhidan)
- A Lesson in Despair (Jingyang Woods)
- Journey to the Jade Palace (City of Chang'an)
- The Emperor's Clay Soldiers (City of Chang'an) (2 Attribute Points)
- Terra Cottas At Large (City of Chang'an)
- Behind the Waterfall (Jinghe River Valley)
- A General in Repose (Quinba Bamboo Forest)
- The Hermit Mage (Village of Binxan)
- Three Sisters (Qiyun Ascent / Jinghe Wetlands)
- Under Wusao Mountain (The Jade Palace)
- Olympus (Typhon's Prison)
Act IV[]
- A Mysterious Message (Temple of Apollo)
- A Crab Story (City of Rhodes)
- An Impossible Task (City of Rhodes) (reward: an arcane formula)
- The Torch-Lighter's Gauntlet (Coastal Asomata) (reward: an arcane formula)
- Outpost in the Woods (Ixian Woods)
- Medea's Price (Medea's Grove)
- The Stolen Sigil (Medea's Grove)
- The Wealth of Ancient Kings (Medea's Grove)
- Lampido's Potion (Medea's Grove) (+Strength, +Health)
- The Treasure Hunters (Tsakonian Ruins)
- The Road to Hades (Medea's Grove)
- Among the Ruins (Epirus ~ Refugee Camp)
- A Dangerous Mission (Epirus ~ Refugee Camp)
- The Enemy's Captain (Epirus ~ Refugee Camp)
- The Stygian Lurker (The River Styx) (+Strength, +Intelligence, +Dexterity)
- One Who Would Lead (The River Styx)
- Judgment of the Living (New Road) (reward: an arcane formula)
- Hades' Treasury (Lower City of Lost Souls - Hades Treasury)
- The Dust of a Titan (Upper City of Lost Souls) (2 Skill Points)
- Eurydice and Orpheus (Upper City of Lost Souls)
- An Invitation (Upper City of Lost Souls)
- The Necromanteion (Upper City of Lost Souls)
- Admetus Among the Dead (Prisoner's Camp)
- An Inside Source (Upper City of Lost Souls)
- The Battle for Elysium (Hall of Judgment)
- The Siege Striders (Aetolian Polis)
- Flight of the Messenger (Aetolian Polis)
- The Achaean Pass (Delian Meadows)
- A Noisy Diversion (Argolis)
- The Immortal Throne (Argolis)
- The Shards of Erebus (Argolis)
- Hades' Generals (Argolis) (+x% Total Damage)
Act V[]
- Troubles of a New Age (City of Corinth)
- Festivities (City of Corinth)
- Sciron (City of Corinth)
- A Northern Contact (City of Corinth) (Lesser Artifact)
- The Warrior Princess (City of Corinth)
- The Power of Nerthus (Glauberg)
- Wine from the Rhine (Rhine Valley)
- The Troubled Son (Glauberg)
- Celtic Plaid (Glauberg)
- Little Friends (Weser Uplands)
- The Trapped Nixie (Wild Heathlands) (1 Skill Point)
- The Kornwyf's Scythe (Wild Heathlands)
- Scandia under Siege (King Gylfi's Hall)
- Giesel (Birch Forest)
- Fir Cone Liquor (Shores of Scandia)
- The Restless King (King Gylfi's Settlement)
- The Magic Cauldron (King Gylfi's Settlement)
- The Survivor (Birch Forest)
- The Rescue (King Gylfi's Hall)
- Dvergar History (Kaupangr) (2 Skill Points)
- Squabbling Merchants (Kaupangr)
- The Craftsman's Passion (Icthian Fjord)
- Legendary Craftsmanship (Master Forge Chamber) (affix added to epic/legendary equipment)
- The Wisest Being (Valhöll)
- The Burning Sword (Mimer's Maze)
Atlantis[]
- The City of Atlas (City of Rhodes)
- The Mysterious Artifacts
- The Exterminator (Atlantis Lower District)
- Ancient Craft (Atlantis Lower District)
- The Letter (Atlas Highlands)
- The Secret Depot (Atlas Mountains)
- Of Goats and Bards (Atlas Mountains)
- The Foraging Mission (Mud Shoals)
- Friends Like These (Atlantis Wilderness)
- A Score to Settle (Atlantis Lower District)
Act VI[]
- A Strange Land
- The Root of the Problem
- Monkey Business
- A Book and its Cover
- The Council of Three
- Emperor Yao's Bell
- Love and Loss
- Seeking An Audience
- Lust for Jade
- Fire and Gold
- Heavenly lovers
- Maze of Mirages
- A Familiar Face
- Shadowstone of Anubis
- No Peace for the Fallen
- A Venom Most Foul
- A God No More
- The Phoenix in the Frog
- Just Desserts